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HelpTest ID TRECS T-Cell Receptor Excision Circles Analysis, Blood
Additional Testing Requirements
This assay is useful for evaluating thymic output, and for longitudinal assessment of thymic function.
For comprehensive assessment of thymic function in pediatric patients and/or individuals who have received hematopoietic stem cell transplantation, order this test together with CD4RT / CD4 T-Cell Recent Thymic Emigrants, Blood.
Shipping Instructions
Specimens must be received in the laboratory on weekdays and by 4 p.m. on Friday. Collect and package specimen as close to shipping time as possible.
It is recommended that specimens arrive within 24 hours of collection.
Samples arriving over the weekend or on observed holidays may be canceled.
Necessary Information
Ordering physician's name and phone number are required.
TREC Assay Patient Information (T589) is required. Testing will proceed without the form; however, results will be held under the information is received.
Specimen Required
For serial monitoring, it is recommended to perform specimen collection at the same time of day, if possible.
Supplies: Ambient Shipping Box-Critical Specimens Only (T668)
Container/Tube: Lavender top (EDTA)
Specimen Volume:
Adults: 10 mL
Pediatrics
-Preferred volume for >1 year: 5 mL
-Preferred volume for ≤1 year old: 3 mL
Collection Instructions:
1. Do not collect specimen using a butterfly needle.
2. Send whole blood specimen in original tube. Do not aliquot.
Forms
TREC Assay Patient Information (T589) is required
Useful For
Measuring T-cell output or reconstitution (thymopoiesis) following hematopoietic cell transplantation or highly active antiretroviral therapy
Evaluating thymic function in patients with cellular or combined inborn errors of immunity (formerly primary immunodeficiencies), or receiving immunotherapy or cancer vaccines
Assessing T-cell recovery following thymus transplants for DiGeorge syndrome
Special Instructions
Method Name
Real-Time Quantitative Polymerase Chain Reaction (PCR)
Reporting Name
TREC Analysis, BSpecimen Type
Whole Blood EDTASpecimen Minimum Volume
Adults: 10 mL
Pediatrics: 1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood EDTA | Ambient | 48 hours | PURPLE OR PINK TOP/EDTA |
Reference Values
The appropriate age-related reference values will be provided on the report.
Day(s) Performed
Varies
Report Available
6 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81479-Unlisted molecular pathology procedure
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TRECS | TREC Analysis, B | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 615825 | TREC Copies | 62320-7 |
| 615822 | CD3 T Cells | 8122-4 |
| 615823 | CD4 T Cells | 24467-3 |
| 615824 | CD8 T Cells | 14135-8 |
| 616642 | Previous Run Date | 93126-1 |
| 616646 | Previous run TREC Copies | 93126-1 |
| 616643 | Previous run CD3 T Cells | 93126-1 |
| 616644 | Previous run CD4 T Cells | 93126-1 |
| 616645 | Previous run CD8 T Cells | 93126-1 |
| 615826 | Interpretation | 69047-9 |
| 615827 | Additional Information | 48767-8 |
| 615828 | Method | 85069-3 |
| 615829 | Disclaimer | 62364-5 |
| 615830 | Released By | 18771-6 |