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HelpTest ID THSCM Thyroid Function Cascade, Serum
Useful For
Screening for a diagnosis of thyroid disease
Special Instructions
Method Name
Electrochemiluminescent Immunoassay
Reporting Name
Thyroid Function Cascade, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days | ||
| Ambient | 72 hours |
Reference Values
0-5 days: 0.7-15.2 mIU/L
6 days-2 months: 0.7-11.0 mIU/L
3-11 months: 0.7-8.4 mIU/L
1-5 years: 0.7-6.0 mIU/L
6-10 years: 0.6-4.8 mIU/L
11-19 years: 0.5-4.3 mIU/L
≥20 years: 0.3-4.2 mIU/L
Day(s) Performed
Monday through Sunday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84443
84439 (if appropriate)
84480 (if appropriate)
86376 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| THSCM | Thyroid Function Cascade, S | 11579-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| STSHC | TSH, Sensitive, S | 11579-0 |
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| STSHC | TSH, Sensitive, S | Yes, (order STSH) | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| FRT4C | T4 (Thyroxine), Free, S | Yes, (order FRT4) | No |
| TPOC | Thyroperoxidase Ab, S | Yes, (order TPO) | No |
| T3C | T3 (Triiodothyronine), Total, S | Yes, (order T3) | No |
Testing Algorithm
If thyrotropin (TSH, formerly thyroid-stimulating hormone) is less than 0.3 mIU/L, then free T4 (thyroxine) is performed at an additional charge.
If FT4 is normal and the TSH is less than 0.1 mIU/L, then T3 (triiodothyronine) is performed at an additional charge.
If TSH is greater than 4.2 mIU/L, then free T4 and thyroperoxidase antibodies are performed at an additional charge.
For more information see Thyroid Function Ordering Algorithm.