Test ID T4 T4 (Thyroxine), Total Only, Serum
Useful For
Monitoring treatment with synthetic hormones (synthetic triiodothyronine [T3] will cause a low total thyroxine [T4])
Monitoring treatment of hyperthyroidism with thiouracil and other anti-thyroid drugs
Index of thyroid function when the thyroxine-binding globulin is normal and non-thyroidal illness is not present
Special Instructions
Method Name
Electrochemiluminescence Immunoassay
Reporting Name
T4 (Thyroxine), Total Only, SSpecimen Type
SerumOrdering Guidance
This test cannot be used in patients receiving treatment with lipid-lowering agents containing dextrothyroxine unless therapy is discontinued for 4 to 6 weeks to allow the physiological state to become reestablished prior to testing.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 7 days | |
Frozen | 30 days |
Reference Values
Pediatric
0-5 days: 5.0-18.5 mcg/dL
6 days-2 months: 5.4-17.0 mcg/dL
3-11 months: 5.7-16.0 mcg/dL
1-5 years: 6.0-14.7 mcg/dL
6-10 years: 6.0-13.8 mcg/dL
11-19 years: 5.9-13.2 mcg/dL
Adult (≥20 years): 4.5-11.7 mcg/dL
For SI unit Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
84436
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
T4 | T4 (Thyroxine), Total Only, S | 83119-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
T4 | T4 (Thyroxine), Total Only, S | 83119-8 |
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Testing Algorithm
For information see Thyroid Function Ordering Algorithm.