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HelpTest ID SCL70 Scl 70 Antibodies, IgG, Serum
Useful For
Evaluating patients with clinical features of systemic sclerosis and in the differential evaluation of individuals at-risk for connective tissue disease with Hep-2 substrate antinuclear antibody positive result, preferably using
antinuclear antibodies
Testing for Scl70 antibodies is not useful who test negative for antinuclear antibody using Hep-2 substrate by IFA.
Special Instructions
Method Name
Multiplex Flow Immunoassay
Reporting Name
Scl 70 Ab, IgG, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Reference Values
<1.0 U (negative)
≥1.0 U (positive)
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86235
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SCL70 | Scl 70 Ab, IgG, S | 47322-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SCL70 | Scl 70 Ab, IgG, S | 47322-3 |
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Testing Algorithm
For more information see Connective Tissue Disease Cascade.