Test ID RP Respiratory Panel, PCR, Nasopharyngeal
Ordering Guidance
This assay is not predicted to detect severe acute respiratory syndrome (SARS)-associated coronavirus or Middle East respiratory syndrome (MERS)-coronavirus.
This test is not intended for otherwise healthy, immunocompetent patients who are likely to have a mild, self-limited respiratory infection. If testing is desired, these patients should be tested using the more targeted diagnostic assays based on their exposure history and clinical presentation.
-FLUNP / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV), Molecular Detection, PCR, Nasopharyngeal Swab
-BPRPV / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR, Varies
-MPRP / Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies
-COVID / Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA Detection, PCR, Varies
It is not recommended that the following tests be concomitantly ordered when this test is ordered:
-FLUNP / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV), Molecular Detection, PCR, Nasopharyngeal Swab
-LADV / Adenovirus, Molecular Detection, PCR, Varies
-LENT / Enterovirus, Molecular Detection, PCR, Varies
-BPRPV / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR, Varies
-MPRP / Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies
-COVID / Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA Detection, PCR, Varies
This test is appropriate for nasopharyngeal swabs only. For bronchoalveolar lavage or bronchial washings specimens, order RPB / Respiratory Panel, PCR, Varies.
Shipping Instructions
Specimens that cannot be shipped refrigerated to Mayo Clinic Laboratories within 3 days (72 hours) should be frozen prior to shipment. Specimens received older than 72 hours (refrigerated) or older than 30 days (frozen) will be canceled.
Specimen Required
Specimen Type: Nasopharyngeal swab
Supplies:
-Culture Swab - Liquid Stuarts/Single Swab (NP Swab) (T515)
-M4-RT (T605)
-Nasopharyngeal Swab (Nylon Mini-Tip Swab) (T861)
Collection Container/Tube: Swab. See Additional Information for acceptable swab.
Submission Container/Tube: Transport medium. See Additional Information for acceptable media.
Specimen Volume: Nasopharyngeal swab in minimum volume of 1 mL of transport media
Collection Instructions:
1. Nasopharyngeal swab specimens should be collected according to standard technique and immediately placed into transport media and submitted for testing.
2. Submit swab in original container.
Additional Information:
If any nasopharyngeal swab or transport media not listed below is utilized, testing may be canceled.
-Acceptable nasopharyngeal (NP) swabs are Copan Rayon Swabs, Copan Nylon Flocked Swabs, Copan Polyester Swabs, Puritan Calcium Alginate Swabs, SteriFlock NP Swab
-Acceptable transport media are Remel M4, Remel M4-RT, Remel M5, Remel M6, BD Universal Viral Transport Media (VTM), Copan Universal Transport Media (UTM), PrimeStore Molecular Transport Medium (MTM)
-Acceptable collection and transport systems are Sigma-Virocult Viral Collection and Transport System (Swab and transport medium), Copan ESwab Sample Collection and Delivery System (Swab and Liquid Amies Medium), and BD ESwab Collection Kit (Flocked swab and Liquid Amies Medium).
Useful For
Rapid detection of respiratory infections caused by the following:
-Adenovirus
-Coronavirus (serotypes HKU1, NL63, 229E, OC43)
- SARS-CoV-2, the causative agent of COVID-19
-Human metapneumovirus
-Human rhinovirus/enterovirus
-Influenza A (H1, H1-2009, H3)
-Influenza B
-Parainfluenza virus (serotypes 1-4)
-Respiratory syncytial virus (RSV)
-Bordetella pertussis
-Bordetella parapertussis
-Chlamydia pneumoniae
-Mycoplasma pneumoniae
This test is not recommended as a test of cure.
Highlights
This test is a multiplex polymerase chain reaction (PCR) test capable of qualitatively detecting DNA or RNA of 22 pathogens (bacteria and viruses) in approximately 1 hour using nasopharyngeal swab specimens.
This test may diagnose infections caused by adenovirus, coronavirus (HKU1, NL63, 229E, OC43), SARS-CoV-2, human metapneumovirus, human rhinovirus/enterovirus, influenza A (H1, H1-2009, H3), influenza B, parainfluenza (1, 2, 3, 4), respiratory syncytial virus, Bordetella pertussis, Bordetella parapertussis, Chlamydia pneumoniae, and Mycoplasma pneumoniae.
Method Name
Multiplex Polymerase Chain Reaction (PCR)
Reporting Name
Respiratory Panel, PCR, NPSpecimen Type
VariesSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Refrigerated (preferred) | 72 hours | |
Frozen | 30 days | ||
Ambient | 4 hours |
Reference Values
Undetected (for all targets)
Performing Laboratory
Mayo Clinic Laboratories in RochesterTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
0202U
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
RP | Respiratory Panel, PCR, NP | 82159-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
SS021 | Specimen Source | 31208-2 |
609644 | Adenovirus | 82160-3 |
609645 | Coronavirus 229E | 82163-7 |
609646 | Coronavirus HKU1 | 82161-1 |
609647 | Coronavirus NL63 | 82162-9 |
609648 | Coronavirus OC43 | 82164-5 |
609649 | SARS Coronavirus-2 | 94565-9 |
609651 | Human Metapneumovirus | 82165-2 |
609650 | Human Rhinovirus/ Enterovirus | 82175-1 |
609652 | Influenza A | 82166-0 |
609653 | Influenza B | 82170-2 |
609654 | Parainfluenza Virus 1 | 82171-0 |
609655 | Parainfluenza Virus 2 | 82172-8 |
609656 | Parainfluenza Virus 3 | 82173-6 |
609657 | Parainfluenza Virus 4 | 82174-4 |
609658 | Respiratory Syncytial Virus | 82176-9 |
609659 | Bordetella parapertussis | 87621-9 |
609660 | Bordetella pertussis | 82179-3 |
609661 | Chlamydia pneumoniae | 82178-5 |
609662 | Mycoplasma pneumoniae | 82177-7 |
609663 | Interpretation | 59464-8 |
NY State Approved
YesTesting Algorithm
If positive for Mycoplasma pneumoniae, M pneumoniae macrolide resistance will be performed at an additional charge.
For more information see Coronavirus Disease 2019 (COVID-19), Influenza, and Respiratory Syncytial Virus Testing Algorithm.
Special Instructions
Day(s) Performed
Monday through SundayReport Available
1 to 2 daysForms
If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
RPMPM | M. pneumoniae Macrolide Resist PCR | Yes | No |