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HelpTest ID PRMB Primidone and Phenobarbital, Serum
Useful For
Assessing compliance
Monitoring for appropriate therapeutic levels of primidone and phenobarbital
Assessing toxicity
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PRIMD | Primidone, S | No | Yes |
| PBR | Phenobarbital, S | Yes | Yes |
Testing Algorithm
Includes phenobarbital determination.
Method Name
PRIMD: Immunoassay
PBR: Kinetic Interaction of Microparticles in a Solution (KIMS)
Reporting Name
Primidone and Phenobarbital, SSpecimen Type
SerumSpecimen Required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reference Values
Primidone
Therapeutic: 5.0-12.0 mcg/mL
Critical value: ≥15.0 mcg/mL
Phenobarbital
Therapeutic: 10.0-40.0 mcg/mL
Critical value: ≥60.0 mcg/mL
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 dayPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
PRIMD-80188
PBR-80184
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PRMB | Primidone and Phenobarbital, S | 10547-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| PBR | Phenobarbital, S | 3948-7 |
| PRIMD | Primidone, S | 3978-4 |
NY State Approved
YesForms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Neurology Specialty Testing Client Test Request (T732)
-Therapeutics Test Request (T831)