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Test ID PERA Preeclampsia sFlt-1/PIGF (Soluble fms-Like Tyrosine Kinase 1/ Placental Growth Factor) Ratio, Serum


Ordering Guidance


The test is indicated for use in pregnant women, with singleton pregnancies (gestational age 23 to 34+6/7 weeks) hospitalized for hypertensive disorders of pregnancy (preeclampsia, chronic hypertension with or without superimposed preeclampsia or gestational hypertension), within 2 weeks of presentation.



Specimen Required


Patient Preparation: For 24 hours before specimen collection, the patient should not receive intravenous heparin.

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Aiding in risk assessment of patients with clinical signs and symptoms consistent with development of preeclampsia with severe features

 

This test is not intended for making a diagnosis of preeclampsia or preeclampsia with severe features.

 

This test is not a stand-alone test for monitoring of hypertensive disorders of pregnancy or for changing treatment, including medication.

Highlights

This test aids in risk assessment of pregnant women between 23 and 34 weeks of gestation with clinical signs and symptoms of hypertensive disorders of pregnancy that might develop preeclampsia with severe features.

 

The sFlt-1/PlGF (soluble fms-like tyrosine kinase 1/placental growth factor) ratio will reported. sFlt-1 and PlGF concentrations will not be individually reported.

Method Name

Immunofluorescent Assay (IFA)

Reporting Name

Preeclampsia sFlt-1/PlGF Ratio, S

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 180 days
  Refrigerated  24 hours

Reference Values

<40

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

0482U

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PERA Preeclampsia sFlt-1/PlGF Ratio, S 74757-6

 

Result ID Test Result Name Result LOINC Value
PERAT sFlt-1/PlGF Ratio 74757-6

NY State Approved

Yes