Test ID NICOU Nicotine and Metabolites, Random, Urine
Useful For
Monitoring tobacco use
Monitoring patients on nicotine-replacement therapy for concurrent use of tobacco products
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Nicotine and Metabolites, USpecimen Type
UrineSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Container/Tube: Plastic urine container
Submission Container/Tube: Plastic, 5-mL tube
Specimen Volume: 3 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 28 days |
| Frozen | 365 days | |
| Ambient | 28 days |
Reference Values
Non-tobacco user with no passive exposure:
Nicotine <5.0 ng/mL
Cotinine
<5.0 ng/mL
Anabasine
<2.0 ng/mL
Nornicotine
<2.0 ng/mL
Day(s) Performed
Monday through Sunday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80323
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NICOU | Nicotine and Metabolites, U | 43125-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 82510 | Nicotine | 3854-7 |
| 21321 | Cotinine | 10366-3 |
| 21324 | Nornicotine | 33917-6 |
| 21323 | Anabasine | 33915-0 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
2 to 5 daysNY State Approved
YesForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.