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HelpTest ID MTXSG Methotrexate Post Glucarpidase, Serum
Useful For
Monitoring methotrexate concentrations post-glucarpidase therapy
Documenting failure to respond that may be due to noncompliance
Guiding dosage adjustments in patients with kidney failure
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Methotrexate Post Glucarpidase, SSpecimen Type
SerumShipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Amber vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into an amber vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | LIGHT PROTECTED |
| Frozen | 14 days | LIGHT PROTECTED | |
| Ambient | 7 days | LIGHT PROTECTED |
Reference Values
Nontoxic drug concentration after 72 hours: <0.1 mcmol/L
Day(s) Performed
Monday through Sunday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80204
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MTXSG | Methotrexate Post Glucarpidase, S | 51602-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 62580 | Methotrexate Post Glucarpidase, S | 51602-1 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
Same day/1 dayNY State Approved
YesForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.