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HelpTest ID MMAP Methylmalonic Acid, Quantitative, Plasma
Useful For
Evaluating children with signs and symptoms of methylmalonic acidemia using plasma specimens
Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Methylmalonic Acid, QN, PSpecimen Type
PlasmaSpecimen Required
Collection Container/Tube:
Preferred: Green top (sodium heparin)
Acceptable: Lavender top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions: Centrifuge and aliquot plasma into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Refrigerated (preferred) | 48 days |
| Ambient | 48 days | |
| Frozen | 48 days |
Reference Values
≤0.40 nmol/mL
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83921
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MMAP | Methylmalonic Acid, QN, P | 13964-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 31927 | Methylmalonic Acid, QN, P | 13964-2 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Disease States
- Homocystinuria
Report Available
3 to 5 daysNY State Approved
YesForms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Benign Hematology Test Request (T755)