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Test ID GLICP CD8 T-Cell Immune Competence Panel, Global, Whole Blood

Useful For

Determining over immunosuppression within the CD8 T-cell compartment, when used on transplant recipients and patients with autoimmune disorders receiving therapy with immunosuppressant agents

Method Name

Flow Cytometry

Reporting Name

CD8 Immune Competence Panel

Specimen Type

WB Sodium Heparin
Whole Blood EDTA


Ordering Guidance


This test requires multiple whole blood specimens to perform all testing. If only one whole blood specimen type is received, only the testing associated with that specimen type will be performed. Be advised that this may change the degree of interpretation received with the report.



Shipping Instructions


Testing is performed Monday through Friday. Specimens not received by 4 p.m. (CST) on Friday may be canceled.

 

Collect and package specimens as close to shipping time as possible. Ship specimens overnight in an Ambient Shipping Box-Critical Specimens Only (T668) following the instructions in the mailer. It is recommended that specimens arrive within 24 hours of collection.

 

Samples arriving on the weekend and observed holidays may be canceled.



Necessary Information


Date and time of collection and ordering healthcare professional name and phone number are required.



Specimen Required


Two separate whole blood specimens, EDTA and (possibly 2 tubes) sodium heparin, are required.

For serial monitoring, it is recommended that specimens are collected at the same time of day.

 

Supplies: Ambient Shipping Box-Critical Specimens Only (T668)

 

Specimen Type: EDTA whole blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions:

1. Send whole blood specimen in original tube. Do not aliquot.

2. Label specimen as TBBS / Quantitative Lymphocyte Subsets: T, B, and Natural Killer (NK) Cells, Blood

Additional Information: For serial monitoring, it is recommended that specimen collection be performed at the same time of day.

 

Specimen Type: Sodium heparin whole blood

Container/Tube: Green top (sodium heparin)

Specimen Volume: 15 mL

Collection Instructions:

1. Send whole blood specimen in original tube. Do not aliquot.

2. Label specimen as GLIC / CD8 T-Cell Immune Competence, Global, Blood


Specimen Minimum Volume

Sodium heparin whole blood: 10 mL
EDTA whole blood: 1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
WB Sodium Heparin Ambient 48 hours GREEN TOP/HEP
Whole Blood EDTA Ambient 52 hours PURPLE OR PINK TOP/EDTA

Reference Values

The appropriate age-related reference values will be provided on the report.

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86355-B cells, total count

86357-Natural killer (NK) cells, total count

86359-T cells, total count

86360-Absolute CD4/CD8 count with ratio

86356 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GLICP CD8 Immune Competence Panel 80721-4

 

Result ID Test Result Name Result LOINC Value
30643 IFN-g 95204-4
3321 CD45 Total Lymph Count 27071-0
30644 CD107a/b 95203-6
3316 % CD3 (T Cells) 8124-0
30645 Interpretation 69052-9
3322 CD3 (T Cells) 8122-4
3319 % CD4 (T Cells) 8123-2
3325 CD4 (T Cells) 24467-3
3320 % CD8 (T Cells) 8101-8
3326 CD8 (T Cells) 14135-8
3318 % CD19 (B Cells) 8117-4
3324 CD19 (B Cells) 8116-6
4054 % CD16+CD56 (NK cells) 8112-5
4055 CD16+CD56 (NK cells) 20402-4
3327 4/8 Ratio 54218-3
6657 Comment 80722-2

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Profile Information

Test ID Reporting Name Available Separately Always Performed
TBBS QN Lymphocyte Subsets: T, B, and NK Yes Yes
GLIC CD8 Immune Competence, B Yes Yes

Report Available

3 to 6 days

Testing Algorithm

When multiple specimen types are required to perform a panel of tests, the laboratory will perform the tests for which the appropriate specimen type was received, and the laboratory will cancel those for which the appropriate specimen was not received.

NY State Approved

No