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Mayo Clinic Laboratories

Test ID FLUPV Lupus Anticoagulant Evaluation with Reflex

Method Name

Clot Detection

Reporting Name

Lupus Anticoagulant Eval w/Reflexes

Specimen Type

Plasma Na Cit


Specimen Required


Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL platelet-poor plasma, in plastic vial

Collection Instructions: Draw blood into a 3.2% sodium citrate (light blue-top) tube. Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl).

Freeze immediately and ship on dry ice.


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 30 days

Reference Values

Lupus Anticoagulant                  Not Detected

 

    This interpretation is based on the following test results:

 

PTT-LA  Screen                      ≤ 40 seconds

DRVVT Screen                       ≤ 45 seconds

 

Day(s) Performed

Monday through Saturday

Performing Laboratory

Quest Diagnostics Nichols Institute

CPT Code Information

85613/ Russell viper venom time (includes venom); diluted

85730/ Thromboplastin time, partial (PTT); plasma

85598/ Platelet neutralization (Hexagonal Phase Confirm)-(if appropriate)

85597/ Platelet neutralization (dRVVT Confirm)-(if appropriate)

85613/dRVVT 1:1 Dilution (if appropriate)

85670/Thrombin Clotting Time (if appropriate)

 

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FLUPV Lupus Anticoagulant Eval w/Reflexes 75515-7

 

Result ID Test Result Name Result LOINC Value
Z0734 Lupus Anticoagulant 75514-0
Z0544 PTT-LA Screen 34571-0
Z0735 DRVVT Screen 6303-2

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FHEXC Hexagonal Phase Confirm No No
FDVTC DRVVT Confirm No No
FDVTX DRVVT 1:1 Mix No No
FCLOT Thrombin Clotting Time No No

Testing Algorithm

If the PTT-LA is prolonged (>40 seconds), then the Hexagonal Phase Confirmation (FHEXC) will be performed at an additional charge.

If the Hexagonal Phase Confirm is positive or weakly positive, a Thrombin Clotting Time (FCLOT) will be performed at an additional charge.

If the DRVVT Screen is prolonged (>45 seconds), then the DRVVT Confirmation (FDVTC) will be performed at an additional charge.

If the DRVVT Confirmation is positive, then the DRVVT 1:1 Mix (FDVTX) will be performed at an additional charge.

Report Available

2 to 8 days

NY State Approved

Yes