Test ID ESTR Estrogen Receptor Immunostain, Technical Component Only
Ordering Guidance
This test includes only technical performance of the immunostain (no pathologist interpretation is performed).
For qualitative immunostain detection of progesterone receptor protein for diagnostic purposes without interpretation, order PROG / Progesterone Receptor Immunostain, Technical Component Only.
For prognostic or predictive immunostain detection of both estrogen and progesterone receptor proteins for primary breast or non-breast specimens with interpretation, order ERPR / Estrogen/Progesterone Receptor, Semi-Quantitative Immunohistochemistry, Manual.
For interpretation and diagnosis of submitted pathology specimens with appropriate additional stains and other ancillary testing, order PATHC / Pathology Consultation.
Additional material may be needed if alternative testing is requested. See the specific specimen requirements for any alternative requested testing.
Shipping Instructions
Attach the green "Attention Pathology" address label (T498) and the pink Immunostain Technical Only label included in the kit to the outside of the transport container.
Specimen Required
Specimen Type: Tissue
Supplies: Immunostain Technical Only Envelope (T693)
Container/Tube: Immunostain Technical Only Envelope
Submit:
-Formalin-fixed, paraffin-embedded tissue block
OR
-2 Unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick
Useful For
Qualitative detection of estrogen receptor alpha protein in a diagnostic setting
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
IHTOI | IHC Initial, Tech Only | No | No |
IHTOA | IHC Additional, Tech Only | No | No |
Method Name
Immunohistochemistry (IHC)
Reporting Name
Estrogen Rec IHC, Tech OnlySpecimen Type
TECHONLYSpecimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
TECHONLY | Ambient (preferred) | |
Refrigerated |
Day(s) Performed
Monday through Friday
Report Available
1 to 3 daysPerforming Laboratory

Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
88342-TC, Primary
88341-TC, If additional IHC
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ESTR | Estrogen Rec IHC, Tech Only | Order only;no result |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
70740 | Estrogen Rec IHC, Tech Only | Bill only; no result |
NY State Approved
YesForms
If not ordering electronically, complete, print, and send a Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763) with the specimen.
Testing Algorithm
For the initial technical component only immunohistochemical (IHC) stain performed, the appropriate bill-only test ID will be reflexed and charged (IHTOI). For each additional technical component only IHC stain performed, an additional bill-only test ID will be reflexed and charged (IHTOA).