Test ID COKEM Cocaine and Metabolites Confirmation, Meconium
Useful For
Detecting in utero drug exposure up to 5 months before birth
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Cocaine and Metabolites, Confirm, MSpecimen Type
MeconiumOrdering Guidance
For chain-of-custody testing, order COKMX / Cocaine and Metabolite Confirmation, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Specimen Minimum Volume
0.3 g (approximately 1/4 teaspoon)
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Meconium | Frozen (preferred) | 21 days | |
Refrigerated | 21 days | ||
Ambient | 72 hours |
Reference Values
Negative
Positives are reported with a quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) result.
Cutoff concentrations for LC-MS/MS testing:
Cocaine: 20 ng/g
Benzoylecgonine: 20 ng/g
Cocaethylene: 20 ng/g
m-Hydroxybenzoylecgonine: 20 ng/g
Day(s) Performed
Monday through Sunday
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
80353
G0480 (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
COKEM | Cocaine and Metabolites, Confirm, M | 69008-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
31859 | Cocaine | 69009-9 |
31860 | Benzoylecgonine | 69010-7 |
31861 | Cocaethylene | 69011-5 |
31862 | m-Hydroxybenzoylecgonine | 69012-3 |
31864 | Interpretation | 69050-3 |
31865 | Chain of Custody | 77202-0 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
2 to 3 daysNY State Approved
YesForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.