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HelpTest ID CMAH Chromosomal Microarray, Hematologic Disorders, Varies
Useful For
Detection and characterization of clonal copy number imbalance and loss of heterozygosity associated with hematologic neoplasms
Assisting in the diagnosis and classification of certain hematologic neoplasms
Evaluating the prognosis for patients with certain hematologic neoplasms
Testing Algorithm
DNA extraction is always performed on the specimen prior to hybridization to the microarray. An unstimulated cell culture will be set up on all specimens with adequate volume and held pending additional testing. If additional testing is requested, such as karyotype analysis or fluorescence in situ hybridization, it will be performed at an additional charge.
The following algorithms are available:
Method Name
Chromosomal Microarray (CMA)
Reporting Name
Chromosomal Microarray, HematologicSpecimen Type
VariesOrdering Guidance
This test is not appropriate for detecting constitutional/congenital copy number changes or regions of excessive homozygosity. If this test is ordered with a reason for testing indicating a constitutional/congenital disorder, the test will be canceled and CMACB / Chromosomal Microarray, Congenital, Blood will be added and performed as the appropriate test.
Shipping Instructions
Advise Express Mail or equivalent if not on courier service.
Necessary Information
1. A reason for testing must be provided for testing to be performed.
2. A pathology report should accompany the specimen. If this information is not available at the time of order, submit as soon as possible for appropriateness of testing and to aid in interpretation of results.
Specimen Required
Submit only 1 of the following specimens:
Specimen Type: Bone marrow
Container/Tube:
Preferred: Green top (sodium heparin)
Acceptable: Lavender top (EDTA)
Specimen Volume: 1-2 mL
Collection Instructions:
1. Invert several times to mix bone marrow.
2. Send bone marrow specimen in original tube. Do not aliquot.
Specimen Type: Whole blood
Container/Tube:
Preferred: Green top (sodium heparin)
Acceptable: Lavender top (EDTA)
Specimen Volume: 7-10 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Minimum Volume
Blood: 2 mL; Bone marrow: 1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Varies | Ambient (preferred) | ||
| Refrigerated | |||
Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Sunday
Report Available
7 to 14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81277
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CMAH | Chromosomal Microarray, Hematologic | 94087-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 54721 | Result Summary | 50397-9 |
| 54722 | Result | 62356-1 |
| 54723 | Nomenclature | 62378-5 |
| 54724 | Interpretation | 69965-2 |
| CG902 | Reason for Referral | 42349-1 |
| CG903 | Specimen | 31208-2 |
| 54725 | Source | 31208-2 |
| 54726 | Method | 85069-3 |
| 53423 | Additional Information | 48767-8 |
| 54727 | Released By | 18771-6 |
NY State Approved
YesSpecial Instructions
Forms
If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.