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Test ID CIFS Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum

Useful For

Confirming the presence of IgG and/or IgG4 antibodies to diagnose pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus

Method Name

Indirect Immunofluorescence Assay (IFA)

Reporting Name

Cutaneous Immfluor. Ab, IgG/IgG4, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reference Values

Negative in normal individuals

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

88346

88350

88350 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CIFS Cutaneous Immfluor. Ab, IgG/IgG4, S In Process

 

Result ID Test Result Name Result LOINC Value
21539 Cell Surface Ab IgG 93233-5
21540 Basement Membrane IgG 29994-1
21542 Primate Split Skin IgG 104832-1
622319 Cell Surface Ab IgG4 In Process
622320 Basement Membrane IgG4 In Process
622322 Primate Split Skin IgG4 In Process
21638 Other 48767-8

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 7 days

NY State Approved

Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
CIFST CIFS Titer, IgG, S No No

Testing Algorithm

If IgG anti-cell surface or anti-basement membrane zone antibodies are present, then the IgG antibody titer will be reflexed and performed at an additional charge.