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Test ID CHIKC Chikungunya Virus, PCR, Molecular Detection, Spinal Fluid


Additional Testing Requirements


Due to the short period in which chikungunya RNA may be detected in cerebrospinal fluid (CSF), testing serum for IgM- and IgG-class antibodies to chikungunya virus is also recommended. See CHIKV / Chikungunya IgM and IgG, Antibody, Serum.



Specimen Required


Collection Container/Tube: Vial number 2

Submission Container/Tube: Sterile screw cap vial

Specimen Volume: 0.5 mL

Collection Instructions: Do not centrifuge or heat inactivate.


Useful For

Qualitative detection of chikungunya virus in cerebrospinal fluid after early symptom onset (ideally <7 days)

 

This test is not recommended for screening healthy patients.

Highlights

This test provides qualitative detection of chikungunya virus RNA from cerebrospinal fluid collected during the acute phase of infection.

 

This test is intended for evaluation of patients with a clinical history and symptoms consistent with chikungunya virus infection.

Method Name

Real-Time Reverse Transcription Polymerase Chain Reaction (RT-PCR)/DNA Probe Hybridization

Reporting Name

Chikungunya Virus, PCR, CSF

Specimen Type

CSF

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

Negative

Reference values apply to all ages.

Day(s) Performed

Tuesday, Thursday

Report Available

Same day/1 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87798

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CHIKC Chikungunya Virus, PCR, CSF 81153-9

 

Result ID Test Result Name Result LOINC Value
603832 Chikungunya Virus, PCR, CSF 81153-9

NY State Approved

Yes

Testing Algorithm

For more information see Mosquito-borne Disease Laboratory Testing

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.