Sign in →

Test ID BETV2 BET v2 (Profilin), IgE, Serum


Ordering Guidance


For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies.

 

BET v2 is also available as part of the PEANT / Peanut, IgE with Reflex to Peanut Components, IgE, Serum. This reflex test includes Ara h2, h1, h3, h6, h9, and Bet v2 (profilin) if the initial Peanut IgE test is detectable.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL for every 5 allergens requested

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Forms

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.

Useful For

Evaluation of patients suspected birch pollen allergy

 

Evaluation of patients with suspected peanut allergy

 

Evaluation of patients with oral allergy syndrome to other pollens or plant-based foods

Highlights

This test determines the relative amount of IgE antibody to the cross-reactive profilin, Bet v2.

 

IgE antibodies to Bet v2 are associated with birch pollen sensitivity and oral allergy syndrome.

 

The presence of IgE antibodies to Bet v2 represents a potential minor marker of peanut allergenicity.

 

Antibodies to Bet v2 may be associated with broad allergenic cross-reactivity with other profilin containing pollens or foods.

Method Name

Fluorescence Enzyme Immunoassay (FEIA)

Reporting Name

BET v2 (Profilin), IgE, S

Specimen Type

Serum

Specimen Minimum Volume

For 1 allergen: 0.3 mL
For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Reference Values

Class

IgE kU/L

Interpretation

0

<0.10

Negative

0/1

0.10-0.34

Borderline/Equivocal

1

0.35-0.69

Equivocal

2

0.70-3.49

Positive

3

3.50-17.4

Positive

4

17.5-49.9

Strongly positive

5

50.0-99.9

Strongly positive

6

≥100

Strongly positive

Concentrations ≥0.70 kU/L (Class 2 and above) will flag as abnormally high.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86008

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BETV2 BET v2 (Profilin), IgE, S 30985-6

 

Result ID Test Result Name Result LOINC Value
BETV2 BET v2 (Profilin), IgE, S 30985-6

NY State Approved

Yes

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days